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The bacteria have developed resistance against many of the drugs available in the market.

Yuhui Shi and Russell Eberhart "A modified particle swarm optimizer" 0- 7803-4869-9198 0.0001998 IEEE.

Conventional hydraulic cylinders are simulated in FLUENT. Singh, "Derivation of design requirements for optimization of a high performance hydrostatic actuation system," International Journal of Fluid Power, vol.

Results show that the small outlet ports are the sources of energy loss in hydraulic cylinders.

Key words: docking, homology modeling, leprosy, M.leprae, molecular, molecular dynamics, ramachandran plot.

Therefore identification of the novel drug target and potent drug can be helpful in better prevention of the disease. Alter et.al, (2008) Leprosy as a genetic model for susceptibility to common infectious disease, Hum Genet 2. (1999)Health Policy and Planning; 14(2): 89-102, Oxford University Press.

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